Super Bowl odds proclaimed Indianapolis as the favorite to win professional football’s biggest prize, but they’ll have their hands full on Saturday when they host a dangerous and hungry Baltimore team.

Ravens vs Colts betting – Saturday, January 16, 8:15 PM ET

The Ravens had three sacks and forced four turnovers in a 33-14 dismantling of New England on the road, and Ray Rice also had a big day, rushing for 159 yards and a pair of scores. Joe Flacco wasn’t called upon much, and he’s been bothered by a hip injury.

The Colts lost their last two after deciding to sit their starters, but Peyton Manning still won his fourth MVP award in a landslide. Manning has continued to put up big numbers while losing some of his weapons, along with a subpar running game. The defense has also been bit by injury, particularly on the corners.

Indianapolis is a 6.5-point favorite in this contest, and they’ve won seven in a row over the Ravens, including a 17-15 victory in Week 10 in Baltimore. The Colts need to shore up their run defense to keep Rice under wraps, but their main priority is Manning. If they can keep their leader on his feet, the Colts always have a chance. After a week of rest, take the Colts this weekend.

Bookmakers odds (bookmaker reviews) pick: Indianapolis -6.5